The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes
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Xkr8-Basigin is a plasma membrane phospholipid scramblase activated by kinases or caspases. We combined cryo-EM and X-ray crystallography to investigate its structure at an overall resolution of 3.8 Å. Its membrane-spanning region carrying 22 charged amino ac... ...