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Monoclonal Antibodies Targeting Alarmins: A New Perspective for Biological Therapies of Severe Asthma

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Alarmins are innate cytokines, including thymic stromal lymphopoietin (TSLP), interleukin-33 (IL-33), and interleukin-25 (IL-25), which are mainly produced by airway epithelium and exert a prominent role in asthma pathobiology. In particular, several environme... ...