NOTCH-mediated ex vivo expansion of human hematopoietic stem and progenitor cells by culture under hypoxia
{{output}}
Activation of NOTCH signaling in human hematopoietic stem/progenitor cells (HSPCs) by treatment with an engineered Delta-like ligand (DELTA1ext-IgG [DXI]) has enabled ex vivo expansion of short-term HSPCs, but the effect on long-term repopulating hematopoietic... ...
