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The mechanism of Annexin A1 to modulate TRPV1 and nociception in dorsal root ganglion neurons

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Background: Annexin A1 (ANXA1) exerts anti-nociceptive effect through ANXA1 receptor formyl peptide receptor 2 (FPR2/ALX (receptor for lipoxin A4), FPR2) at the dorsal root ganglia (DRG) level. However, the mechanisms remain eluc... ...