An in vitro cytotoxicity of glufosfamide in HepG2 cells relative to its nonconjugated counterpart
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Background: Glufosfamide (β-D-glucosylisophosphoramide mustard, GLU) is an alkylating cytotoxic agent in which ifosforamide mustard (IPM) is glycosidically linked to the β-D-glucose molecule. GLU exerted its cytotoxic effect as... ...