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Targeting Rac1 for the prevention of atherosclerosis among U.S. Veterans with inflammatory bowel disease

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Evidence suggests that Ras-related C3 botulinum toxin substrate 1 (Rac1) might be a target in atherosclerotic disease (AD). We hypothesize that due to their ability to inhibit Rac1, thiopurines are associated with a lower risk of AD. We fit a time-dependent co... ...