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Progression of melanoma is suppressed by targeting all transforming growth factor‑β isoforms with an Fc chimeric receptor

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Melanoma is an aggressive type of cancer originating from the skin that arises from neoplastic changes in melanocytes. Transforming growth factor‑β (TGF‑β) is a pleiotropic cytokine and is known to contribute to melanoma progression by inducing the epithel... ...