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Role of human group IIA secreted phospholipase A2 in malaria pathophysiology: Insights from a transgenic mouse model

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We previously showed that injection of recombinant human group IIA secreted phospholipase A2 (hGIIA sPLA2) to Plasmodium chabaudi-infected mice lowers parasitaemia by 20%. Here, we show that transgenic (TG) mice overexpressing hGIIA sPLA2 have a peak of parasi... ...