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Isoform-specific roles of the Drosophila filamin-type protein Jitterbug (Jbug) during development

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Filamins are highly conserved actin-crosslinking proteins that regulate organization of the actin cytoskeleton. As key components of versatile signaling scaffolds, filamins are implicated in developmental anomalies and cancer. Multiple isoforms of filamins exi... ...