Chemoproteomics profiling of surfactin-producing nonribosomal peptide synthetases in living bacterial cells
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Much of our current knowledge on nonribosomal peptide synthetases (NRPSs) is based on studies in which the full NRPS system or each protein domain is expressed in heterologous hosts. Consequently, methods to detect the endogenous activity of NRPSs, under natur... ...