Finite-temperature effect in the O-acylation of (R,S)-propranolol catalyzed by Candida antarctica lipase B
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CalB is a triacylglycerol hydrolase (E.C.3.1.1.3) used in the O-acylation of the beta-adrenergic blocking agent (R,S)-propranolol. The catalytic mechanism involves two steps: enzyme acylation and enzyme deacylation. The enantioselectivity of the O-acylation of... ...