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Autofluorescence as a noninvasive biomarker of senescence and advanced glycation end products in Caenorhabditis elegans

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To assess the utility of autofluorescence as a noninvasive biomarker of senescence in Caenorhabditis elegans, we measured the autofluorescence of individual nematodes using spectrofluorometry. The fluorescence of each worm increased with age. Animals with lowe... ...