Methotrexate Polyglutamates Analysis by Chromatography Methods in Biological Matrices: A Review
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Methotrexate (MTX) is used as an immunosuppressant and antineoplastic drug in clinical practice. MTX is a parent drug and converts to MTX polyglutamates (MTXPGs) to exhibit its biological activity. Clinical studies found that MTXPG levels were associated with ... ...
