Characterizing ligand-induced conformational changes in clinically relevant galectin-1 by HN/H2O (D2O) exchange
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Glycans of cellular glycoconjugates serve as biochemical signals for a multitude of (patho)physiological processes via binding to their receptors (e.g. lectins). In the case of human adhesion/growth-regulatory galectin-1 (Gal-1), small angle neutron scattering... ...