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Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition

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Neuromuscular junctions (NMJs) ensure communication between motor neurons (MNs) and muscle; however, in MN disorders, such as amyotrophic lateral sclerosis (ALS), NMJs degenerate resulting in muscle atrophy. The aim of this study was to establish a versatile a... ...