Feedback Regulation of Cathepsin C by the Propeptide Dipeptides of Granzymes A and B
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Granzymes A and B are activated by proteolytic removal of their N-terminal dipeptides by cathepsin C (dipeptidyl-peptidase I). However, the possible physiological role of the cleaved dipeptides Glu-Lys and Gly-Glu is not yet understood. In this study, adding e... ...
