Disrupting progression of the yeast Hsp90 folding pathway at different transition points results in client-specific maturation defects
{{output}}
The protein molecular chaperone Hsp90 (Heat shock protein, 90 kilodalton) plays multiple roles in the biogenesis and regulation of client proteins impacting myriad aspects of cellular physiology. Amino acid alterations located throughout Saccharomyces cerevisi... ...
