Molecular basis of C-S bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase
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Desulfonation of isethionate by the bacterial glycyl radical enzyme (GRE) isethionate sulfite-lyase (IslA) generates sulfite, a substrate for respiration that in turn produces the disease-associated metabolite hydrogen sulfide. Here, we present a 2.7 Å resolu... ...
