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The Current State of Oncolytic Herpes Simplex Virus for Glioblastoma Treatment

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Glioblastoma (GBM) is a lethal primary malignant brain tumor with no current effective treatments. The recent emergence of immuno-virotherapy and FDA approval of T-VEC have generated a great expectation towards oncolytic herpes simplex viruses (oHSVs) as a pro... ...