Regulatory mechanisms of the bile salt export pump (BSEP/ABCB11) and its role in related diseases
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The bile salt export pump (BSEP/ABCB11) is located on the apical membrane and mediates the secretion of bile salts from hepatocytes into the bile. BSEP-mediated bile salt efflux is the rate-limiting step of bile salt secretion and the main driving force of bil... ...