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SYNTHESIS AND EVALUATION OF WATER-SOLUBLE DIMETHYLAMINOETHYL ETHERS OF METHOXSALEN FOR PROLIFERATIVE SKIN DISORDERS

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The natural product 8-methoxypsoralen (methoxsalen or 8-MOP) in combination with long wavelength ultraviolet light (UVA, 320-400 nm), also referred to as PUVA therapy, is used for the treatment of cutaneous proliferative disorders including psoriasis, vitiligo... ...