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Thiopurine S-methyltransferase and Pemphigus Vulgaris: A Phenotype-Genotype Study

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Background & objective: Thiopurine drugs are considered as a treatment modality in various autoimmune disorders including pemphigus vulgaris (PV). These drugs are metabolized by an enzyme "Thiopurine S-methyl transferase" (TPMT).... ...