Concise Chemoenzymatic Total Synthesis and Identification of Cellular Targets of Cepafungin I
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The natural product cepafungin I was recently reported to be one of the most potent covalent inhibitors of the 20S proteasome core particle through a series of in vitro activity assays. Here, we report a short chemoenzymatic total synthesis of cepafungin I fea... ...
