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In vitro antitumor effect of cucurbitacin E on human lung cancer cell line and its molecular mechanism

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Cucurbitacin E (CuE) is previously reported to exhibit antitumor effect by several means. In this study, CuE acted as a tyrosine kinase inhibitor interfering with the epidermal growth factor receptor/mitogen-activated protein kinase (EGFR/MAPK) signaling pathw... ...