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Through the Looking-Glass: Reevaluating DHEA Metabolism Through HSD3B1 Genetics

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Dehydroepiandrosterone (DHEA) and DHEA sulfate together are abundant adrenal steroids whose physiological effects are mediated through their conversion to potent downstream androgens. 3β-Hydroxysteroid dehydrogenase isotype 1 (3βHSD1) facilitates the rate-li... ...