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NMR mapping of the highly flexible regions of 13C/15N-labeled antibody TTAC-0001-Fab

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Monoclonal antibody (mAb) drugs are clinically important for the treatment of various diseases. TTAC-0001 is under development as a new anti-cancer antibody drug targeting VEGFR-2. As the less severe toxicity of TTAC-0001 compared to Bevacizumab, likely due to... ...