Blood Flow to the Spleen is Altered in a Mouse Model of Spinal Muscular Atrophy
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Spinal muscular atrophy (SMA) is a neuromuscular disorder affecting young children. While pre-clinical models of SMA show small spleens, the same is not true in humans. Here, we show by doppler ultrasonography decreased splenic blood flow in Smn2B/- mice. Furt... ...