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Nonlinear and mixed inhibitory effect of matrine on the cytotoxicity of oligomeric amyloid-β protein

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The formation of amyloid β-protein (1-42) (Aβ42) oligomers and Aβ42 oligomer cytotoxicity are two defining characteristics of the etiology of Alzheimer's disease (AD). In this study, we found that matrine (Mat) could maintain or even enhance the cytotrophic... ...