HIV Tat-mediated induction of autophagy regulates the disruption of ZO-1 in brain endothelial cells
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The blood-brain barrier (BBB) is a tight barrier that is critical for preventing the entry of pathogens and small molecules into the brain. HIV protein Tat (Tat) is known to disrupt the tight junctions of the BBB. Autophagy is an intracellular process that inv... ...
