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Expression of anti-tumor recombinant IgG- and IgE-like genes in eukaryotic cells

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The tandem of humanized variable VL and VH genes (ScFv fragment 4D5) possessing a high affinity to the HER-2/neu oncogene (the epidermal growth factor receptor expressed in many types of human tumors) was attached through a flexible linker to the second exon o... ...