Is there a link between IL-23/IL-17 and developmental pathways such as the Wnt and Hedgehog pathway?
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Recent experimental evidence suggests that IL-23 may induce spondyloarthropathy by acting on entheseal resident "innate-like" T cells. These cells express IL-23R and respond to IL-23 by secreting inflammatory cytokines such as IL-6 and IL-17 as well as IL-22 w... ...