Twenty years of research on the DFS70/LEDGF autoantibody-autoantigen system: many lessons learned but still many questions
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The discovery and initial characterization 20 years ago of antinuclear autoantibodies (ANAs) presenting a dense fine speckled (DFS) nuclear pattern with strong staining of mitotic chromosomes, detected by indirect immunofluorescence assay in HEp-2 cells (HEp-2... ...