MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome
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Mitochondrial D2HGDH and L2HGDH catalyze the oxidation of D-2-HG and L-2-HG, respectively, into αKG. This contributes to cellular homeostasis in part by modulating the activity of αKG-dependent dioxygenases. Signals that control the expression/activity of D2... ...
