Polynuclear Ruthenium Amines Inhibit K2P Channels via a "Finger in the Dam" Mechanism
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The trinuclear ruthenium amine ruthenium red (RuR) inhibits diverse ion channels, including K2P potassium channels, TRPs, the calcium uniporter, CALHMs, ryanodine receptors, and Piezos. Despite this extraordinary array, there is limited information for how RuR... ...
