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Development of a physiologically-based pharmacokinetic model for cyclosporine in Asian children with renal impairment

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This study aimed to assess the pharmacokinetics of cyclosporine A (CsA) in Asian children with renal impairment (RI) by developing a physiologically-based pharmacokinetic (PBPK) model with Simcyp Simulator. The PBPK model of Asian children with RI was develope... ...