Lipopolysaccharide Increases Cortical Kynurenic Acid and Deficits in Reference Memory in Mice
{{output}}
Kynurenic acid (KYNA), a glial-derived metabolite of tryptophan metabolism, is an antagonist of the alpha 7 nicotinic acetylcholine receptor and the glycine-binding site of N-methyl-d-aspartate (NMDA) receptors. Kynurenic acid levels are increased in both the ... ...