EPAC1 and EPAC2 promote nociceptor hyperactivity associated with chronic pain after spinal cord injury
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Chronic pain following spinal cord injury (SCI) is associated with electrical hyperactivity (spontaneous and evoked) in primary nociceptors. Cyclic adenosine monophosphate (cAMP) signaling is an important contributor to nociceptor excitability, and knockdown o... ...
