Disruption of Broad Epigenetic Domains in PDAC Cells by HAT Inhibitors
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The spreading of epigenetic domains has emerged as a distinguishing epigenomic phenotype for diverse cell types. In particular, clusters of H3K27ac- and H3K4me3-marked elements, referred to as super-enhancers, and broad H3K4me3 domains, respectively, have been... ...
