The novel high-frequency variant of TRPV3 p.A628T in East Asians showing faster sensitization in response to chemical agonists
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TRPV3, a member of the thermosensitive Ca2+-permeable TRPV channel subfamily expressed in skin and sensory nerves, is also activated by chemical agonists such as 2-aminoethyl diphenylborinate (2-APB). Repetitive stimuli induce sensitization of TRPV3 activation... ...