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Novel urate transporter 1 (URAT1) inhibitors: a review of recent patent literature (2016-2019)

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Introduction: Human urate transporter 1 (URAT1), which is an influx transporter protein, is located at the apical surface of renal tubular cells and presumed to be the major transporter responsible for the reabsorption of urate from blood. About 90% of patient... ...