Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1
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Anti-silencing function 1 (ASF1) is a conserved H3-H4 histone chaperone involved in histone dynamics during replication, transcription, and DNA repair. Overexpressed in proliferating tissues including many tumors, ASF1 has emerged as a promising therapeutic ta... ...
