Genome. 2020 Mar;63(3):133-143. doi: 10.1139/gen-2019-0022 Q31.72025

Genome-wide association study provides insights into the genetic architecture of bone size and mass in chickens

全基因组关联研究为揭示鸡骨大小和质量的遗传结构提供新见解翻译改进

Jun Guo^{1 1}, Liang Qu^{1 1}, Tao-Cun Dou^{1 1}, Man-Man Shen^{1 1}, Yu-Ping Hu^{1 1}, Meng Ma^{1 1}, Ke-Hua Wang^{1 1}

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¹ Jiangsu Institute of Poultry Science, Key Laboratory for Poultry Genetics and Breeding of Jiangsu province, Yangzhou, Jiangsu, 225125, China.

DOI: 10.1139/gen-2019-0022 PMID: 31794256

摘要 Ai翻译

Bone size is an important trait for chickens because of its association with osteoporosis in layers and meat production in broilers. Here, we employed high density genotyping platforms to detect candidate genes for bone traits. Estimates of the narrow heritabilities ranged from 0.37 ± 0.04 for shank length to 0.59 ± 0.04 for tibia length. The dominance heritability was 0.12 ± 0.04 for shank length. Using a linear mixed model approach, we identified a pr... ...点击完成人机验证后继续浏览

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期刊名：Genome

缩写：GENOME

ISSN：0831-2796

e-ISSN：1480-3321

IF/分区：1.7/Q3

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Genome-wide association study provides insights into the genetic architecture of bone size and mass in chickens

全基因组关联研究为揭示鸡骨大小和质量的遗传结构提供新见解翻译改进

Genome-wide association study of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes

极端高骨量的全基因组关联研究：常见变异对极端骨密度表型的影响及潜在的新骨密度相关基因

Genome-wide association study identifies HMGN3 locus for spine bone size variation in Chinese

全基因组关联研究鉴定到中国人群中与椎体骨大小变异相关的HMGN3位点

Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study

全基因组关联研究鉴定PLCL1基因为女性髋骨大小差异的遗传位点

Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns

针对免疫球蛋白G糖基化模式的大规模遗传关联研究

A genome-wide association study identifies new genes associated with developmental dysplasia of the hip

全基因组关联研究发现与发育性髋关节发育不良相关的新的易感基因

Genome-wide association study of antisocial personality disorder

精神分裂症的功能表型遗传研究

Risk of lower respiratory tract infections: a genome-wide association study with Mendelian randomization analysis in three independent European populations

下呼吸道感染的风险：在三个独立的欧洲人群中进行孟德尔随机化分析的全基因组关联研究

A Genome-Wide Association Study into the Aetiology of Congenital Solitary Functioning Kidney

单侧肾脏发生的遗传背景的全基因组关联分析研究

Genome-wide association study provides insights into the genetic architecture of bone size and mass in chickens

全基因组关联研究为揭示鸡骨大小和质量的遗传结构提供新见解 翻译改进

Genome-wide association study of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes

极端高骨量的全基因组关联研究：常见变异对极端骨密度表型的影响及潜在的新骨密度相关基因

Genome-wide association study identifies HMGN3 locus for spine bone size variation in Chinese

全基因组关联研究鉴定到中国人群中与椎体骨大小变异相关的HMGN3位点

Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study

全基因组关联研究鉴定PLCL1基因为女性髋骨大小差异的遗传位点

Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns

针对免疫球蛋白G糖基化模式的大规模遗传关联研究

A genome-wide association study identifies new genes associated with developmental dysplasia of the hip

全基因组关联研究发现与发育性髋关节发育不良相关的新的易感基因

Genome-wide association study of antisocial personality disorder

精神分裂症的功能表型遗传研究

Risk of lower respiratory tract infections: a genome-wide association study with Mendelian randomization analysis in three independent European populations

下呼吸道感染的风险：在三个独立的欧洲人群中进行孟德尔随机化分析的全基因组关联研究

A Genome-Wide Association Study into the Aetiology of Congenital Solitary Functioning Kidney

单侧肾脏发生的遗传背景的全基因组关联分析研究

全基因组关联研究为揭示鸡骨大小和质量的遗传结构提供新见解翻译改进