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Solvation Free Energy Simulation for Rosmarinic Acid Extraction from Orthosiphon stamineus

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This study was aimed to extract rosmarinic acid from Orthosiphon stamineus Benth. (Lamiaceae) in high yield. The mixture of chloroform-ethyl acetate (70:30) was chosen as the solvent system because rosmarinic acid gave the lowest solvation free energy in that ... ...