Conjugating doxorubicin to polymannose: a new strategy for target specific delivery to lung cancer cells
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As mannose receptors are known to be over-expressed in cancer cells, we synthesized polymannose-doxorubicin (PM-DOX) conjugates with the objective of targeting the drug to cancer cells. DOX was conjugated to oxidized PM through Schiff's linkages to obtain PM-D... ...
