Deletion of organic cation transporter Oct3 promotes hepatic fibrosis via upregulation of TGFβ
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Organic cation transporters (OCT) are responsible for the intracellular uptake and detoxification of a broad spectrum of endogenous and exogenous substrates. OCTs are downregulated in cholestasis, fibrosis, and hepatocellular carcinoma, but the underlying mole... ...