A tale of ligands big and small: an update on how pentameric ligand-gated ion channels interact with agonists and proteins
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Pentameric ligand-gated ion channels (pLGICs, also known as Cys-loop receptors) are a large family of ion channels expressed in all Bilateria and in several groups of bacteria and archaea. They are activated by small-molecule neurotransmitters to mediate fast ... ...
