Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents
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A large number of glucagon-like-peptide-1 (GLP-1)- and peptide-YY (PYY)-producing L cells are located in the colon, but little is known about their contribution to whole body metabolism. Since bile acids (BAs) increase GLP-1 and PYY release, and since BAs spil... ...