The antitumor efficacy of monomeric disintegrin obtustatin in S-180 sarcoma mouse model
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Obtustatin, isolated from the Levantine Viper snake venom (Macrovipera lebetina obtusa -MLO), is the shortest known monomeric disintegrin shown to specifically inhibit the binding of the α1β1 integrin to collagen IV. Its oncostatic effect is due to the inhib... ...
