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Suppression of Syk activation by resveratrol inhibits MSU crystal-induced inflammation in human monocytes

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Monosodium urate (MSU) crystals are an endogenous sterile particulate that has been identified as a potent damage-associated molecular pattern (DAMP). In humans, the induction of IL-1β production through MSU-induced NLRP3 inflammasome activation in monocytes/... ...