Intestinal TGR5 agonism improves hepatic steatosis and insulin sensitivity in Western diet-fed mice
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Takeda G protein-coupled receptor 5 (TGR5) agonists induce systemic release of glucagon-like peptides (GLPs) from intestinal L cells, a potentially therapeutic action against metabolic diseases such as nonalcoholic steatohepatitis (NASH), nonalcoholic fatty li... ...